Le Merre Lab

Comment redessiner la carte du cerveau en écoutant les neurones un par un ? (How to redraw the brain's map by listening to the activity of single neurons?)

Guyon N, Le Merre P

médecine/sciences 2026;42(6-7):544-547

10.1051/medsci/2026097

Capturing Spatially Organized Oscillatory Cliques as Signatures of Neuronal Assemblies

Heining K, Le Merre P, Lundqvist M, Carlén M

bioRxiv 2026.03.14.711812

10.64898/2026.03.14.711812

A prefrontal cortex map based on single-neuron activity

Le Merre P*, Heining K*, Slashcheva M, Jung F, Moysiadou E, Guyon N, Yahya R, Park H, Wernstal F, Carlén M (*Equal contribution)

Nature Neuroscience 2026;29:673-681

10.1038/s41593-025-02190-z

Claustrum and dorsal endopiriform cortex complex cell-identity is determined by Nurr1 and regulates hallucinogenic-like states in mice

Mantas I, Flais I, Masarapu Y, Ionescu T, Frapard S, Jung F, Le Merre P, Saarinen M, Tiklova K, Salmani BY, Gillberg L, Zhang X, Chergui K, Carlen M, Giacomello S, Hengerer B, Perlmann T, Svenningsson P

Nature Communications 2024; 15(1):8176

10.1038/s41467-024-52429-9

Esr1+ hypothalamic-habenula neurons shape aversive states

Calvigioni D*, Fuzik J*, Le Merre P*, Slashcheva M, Jung F, Ortiz C, Lentini A, Csillag V, Graziano M, Nikolakopoulou I, Weglage M, Lazaridis I, Kim H, Lenzi I, Park H, Reinius B, Carlen M, Meletis K

Nature Neuroscience 2023;26(7):1245-1255

10.1038/s41593-023-01367-8

The mouse prefrontal cortex: Unity in diversity

Le Merre P*, Ahrlund-Richter S*, Carlen M

Neuron 2021;109(12):1925-1944

10.1016/j.neuron.2021.03.035

A latent lineage potential in resident neural stem cells enables spinal cord repair

Llorens-Bobadilla E, Chell JM, Le Merre P, Wu Y, Zamboni M, Bergenstrahle J, Stenudd M, Sopova E, Lundeberg J, Shupliakov O, Carlen M, Frisen J

Science 2020;370(6512):73

10.1126/science.abb8795

Reward-Based Learning Drives Rapid Sensory Signals in Medial Prefrontal Cortex and Dorsal Hippocampus Necessary for Goal-Directed Behavior

Le Merre P, Esmaeili V, Charrière E, Galan K, Salin P-A, Petersen CCH, Crochet S

Neuron 2018;97(1):83-91.e5

10.1016/j.neuron.2017.11.031

Highly Dynamic Spatiotemporal Organization of Low-Frequency Activities During Behavioral States in the Mouse Cerebral Cortex

Fernandez LMJ; Comte J-C; Le Merre P; Lin J-S; Salin P-A; Crochet S

Cerebral Cortex 2017;27(12):5444-5462

10.1093/cercor/bhw311